The offspring of Satan are all who oppose God’s plan of redemption – Cain, Ham, the Canaanites, and the pharaoh in Egypt who will end up enslaving God’s people for over four hundred years. God orchestrates a plan to fix creation by working through the womb of women. Ultimately, a descendent of Eve will “bruise” (or “crush”) the head of Satan. That’s the promise of Genesis 3:15. And that’s why this verse is the first of many so-called messianic promises of the Bible.
– Sprinkle, Preston; Charis: God’s Scandalous Grace for Us; David C. Cook Publishing; Colorado Springs, CO; Kindle version; copyright 2014; page 50-51