For this reason [that the original manuscripts are unavailable] many scoff at the doctrine of inerrancy, saying it is a moot point since it cannot be verified or falsified without access to the original manuscripts. This criticism misses the point altogether. We carry no brief for the inspiration of copyists or translators. The original revelation is the chief concern of the doctrine of inerrancy. Though we do not possess the autographs themselves, we can reconstruct them with remarkable accuracy. The science of textual criticism demonstrates that the existing text is remarkably pure and exceedingly reliable.
– Sproul, R.C.; Grace Unknown: The Heart of Reformed Theology; Baker Books; Grand Rapids, MI; copyright 1997; p. 50